🧬 Chapter 8: Microbes in Human Welfare– Class 12 Biology Notes | NCERT + NEET Focus

Rashmi Mishra
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🌸Chapter 8

Microbes in Human Welfare

(Notes) 

🔷 1. Introduction

  • Microbes (Microorganisms): Tiny living organisms invisible to the naked eye.
  • Types of Microbes:
    • Bacteria
    • Fungi
    • Protozoa
    • Algae
    • Viruses
    • Viroids
    • Prions

Though some microbes cause diseases, many are beneficial to humans and play important roles in food processing, industrial production, sewage treatment, agriculture, etc.


🔷 2. Microbes in Household Products

🍶 (A) Fermented Beverages

  • Microbes are used to convert sugar into alcohol by the process of fermentation.
  • Yeast (Saccharomyces cerevisiae) is commonly used.

Examples:

Beverage

Substrate

Organism

Wine

Grapes (fruit juice)

Saccharomyces cerevisiae

Beer

Barley malt

Saccharomyces cerevisiae

Whisky, Rum, Brandy

Molasses or grains

Saccharomyces cerevisiae

Note: Different beverages have different alcohol content depending on substrate and distillation process.


🍞 (B) Fermented Foods

(i) Bread Making:

  • Yeast → ferments dough → CO₂ produced → dough rises → soft and spongy texture.

(ii) Idli, Dosa, Dhokla:

  • Fermentation by Lactic Acid Bacteria (LAB) and Yeast.
  • Increases digestibility and nutrient value.

🥛 (C) Curd Formation:

  • Curd prepared by Lactic Acid Bacteria (Lactobacillus / Lactococcus).
  • LAB ferments lactose (milk sugar) into lactic acid.
  • Lactic acid → coagulates milk protein (casein) → curd.
  • Improves nutritional quality and vitamin B12 content.

NEET Tip:

Starter culture of curd contains Lactobacillus acidophilus.


🧈 (D) Other Dairy Products:

  • Cheese: Different microbes give characteristic texture and flavour.
    • Roquefort cheese → ripened by Penicillium roqueforti.
    • Swiss cheese → by Propionibacterium shermanii (produces CO₂ → holes in cheese).

🔷 3. Microbes in Industrial Products

Industrial microbiology involves large-scale microbial growth in fermenters to produce useful products.

Major Industrial Products:

Product

Example Organism

Use

Alcoholic Beverages

Saccharomyces cerevisiae

Drinks, solvents

Antibiotics

Penicillium notatum, Streptomyces spp.

Kill/inhibit bacteria

Organic Acids

Aspergillus niger (citric acid), Acetobacter aceti (acetic acid), Clostridium butylicum (butyric acid)

Food, industry

Enzymes

Aspergillus spp., Bacillus spp.

Detergents, textile, food

Cyclosporin A

Trichoderma polysporum

Immunosuppressant (used in organ transplantation)

Statins

Monascus purpureus

Lowers blood cholesterol


🧫 (A) Antibiotics

  • Definition: Chemical substances produced by microorganisms that kill or inhibit growth of other microbes.
  • First antibiotic: Penicillin discovered by Alexander Fleming (1928) from Penicillium notatum.
  • Florey and Chain → developed it for large-scale use (WWII).
  • Importance: Revolutionized medicine; saved millions of lives.

Examples:

·        Streptomycin (from Streptomyces griseus)

·        Tetracycline, Erythromycin, Chloramphenicol, etc.


⚗️ (B) Fermenters

  • Large vessels (stainless steel) used for industrial-scale microbial culture under controlled conditions (temperature, aeration, pH).
  • Products extracted, purified, and commercialized.

🔷 4. Microbes in Sewage Treatment

🧴 (A) Sewage:

  • Wastewater from homes, hospitals, industries → contains organic matter & microbes.

🧪 (B) Sewage Treatment Steps:

(i) Primary Treatment (Physical)

  • Removal of large and floating particles by filtration & sedimentation.
  • Solids → primary sludge
  • Supernatant → effluent (used in secondary treatment).

(ii) Secondary Treatment (Biological)

  • Effluent passed into aeration tanksaerobic microbes oxidize organic matter → CO₂ + water.

👉 Involves formation of Activated Sludge:

  • Microbes form flocs (masses of bacteria + fungal filaments).
  • Effluent → aerated → microbes consume organic matter.
  • After settling → activated sludge formed (used as inoculum).

Some activated sludge → used to treat new sewage; remainder → digested anaerobically → biogas.

(iii) Anaerobic Sludge Digestion:

  • Methanogens (Archaebacteria) like Methanobacterium act on sludge.
  • Produce biogas (CH₄ + CO₂ + H₂).

Diagram (for Boards & NEET):

Sewage Treatment → Primary (Physical) → Secondary (Biological)

                                             

             Primary Sludge           Activated Sludge → Biogas


🔷 5. Microbes in Production of Biogas

  • Biogas: Mixture of methane (CH₄), CO₂, and H₂ produced by microbial anaerobic digestion.

(A) Biogas Production Process

1.   Slurry of cow dung + water → put in biogas plant digester.

2.   Anaerobic digestion by methanogenic bacteria → Methanobacterium.

3.   Biogas collected from top chamber and used as fuel.

Steps of Digestion:

1.   Hydrolysis

2.   Acid formation

3.   Methane formation

Uses:

  • Cooking, lighting, running engines.
  • Reduces pollution and provides manure.

Developed in India by Indian Agricultural Research Institute (IARI) and Khadi and Village Industries Commission (KVIC).


🔷 6. Microbes as Biocontrol Agents

🐞 Definition:

Use of natural living organisms (microbes, insects, etc.) to control pests and diseases.

Examples:

Biocontrol Agent

Organism

Target / Use

Bacillus thuringiensis (Bt)

Bacterium

Insect pest control (kills larvae of butterfly, moth, beetle)

Trichoderma spp.

Fungi

Free-living fungi in root region → control fungal pathogens

Ladybird beetle, Dragonfly

Insects

Eat aphids and mosquitoes (biological pest control)

Bt toxin gene has been used to produce Bt cotton (GM crop) resistant to bollworm.


🔷 7. Microbes as Biofertilisers

🌱 Definition:

Microorganisms that increase soil fertility and plant growth by enriching nutrient availability.

Major Categories:

(i) Bacteria

  • Rhizobium → lives symbiotically in root nodules of leguminous plants → fixes nitrogen.
  • Azospirillum, Azotobacterfree-living nitrogen fixers.

(ii) Cyanobacteria (Blue-green algae)

  • Anabaena, Nostoc, Oscillatoria → photosynthetic, fix N₂.
  • Found in paddy fields → increase yield naturally.

(iii) Fungi (Mycorrhiza)

  • Glomus forms symbiotic association with plant roots.
  • Help in phosphate absorption, water uptake, and disease resistance.

(iv) Biofertilizer Mixtures

  • Contain combinations like Rhizobium + Phosphate-solubilizing bacteria + Azotobacter for balanced nutrient supply.

🔷 8. Summary Table (NEET Revision Sheet)

Role

Microbe

Application

Curd

Lactobacillus

Milk → Curd

Bread

Saccharomyces cerevisiae

Dough fermentation

Swiss Cheese

Propionibacterium shermanii

CO₂ → holes

Antibiotic

Penicillium notatum

Penicillin

Organic Acid

Aspergillus niger

Citric acid

Immunosuppressant

Trichoderma polysporum

Cyclosporin A

Cholesterol lowering

Monascus purpureus

Statins

Sewage Treatment

Methanobacterium

Biogas

Biofertiliser

Rhizobium

N₂ fixation

Bt Toxin

Bacillus thuringiensis

Biopesticide


🔷 9. Important Diagrams (for Board Exam)

1.   Sewage treatment plant (aeration tank)

2.   Biogas plant structure

3.   Root nodule showing Rhizobium

4.   Activated sludge process (flow chart)


🔷 10. NEET & Board Important Keywords

Fermentation, Antibiotic, Flocs, Activated sludge, Methanogens, Biogas, Biofertiliser, Mycorrhiza, Bt toxin, Cyclosporin A, Statins, Lactic acid bacteria.


🧠 Important Board / NEET Questions

1.   What is the role of Lactobacillus in milk?
→ Converts lactose into lactic acid; coagulates milk → curd formation.

2.   Name one methanogen and its function.
Methanobacterium → produces biogas during anaerobic digestion.

3.   What are antibiotics? Give one example.
→ Chemical substances from microbes that kill/inhibit other microbes; e.g., Penicillin.

4.   What is the function of Trichoderma?
→ Fungal biocontrol agent → suppresses pathogens in root region.

5.   What are biofertilisers? Give examples.
→ Microbes that enhance soil fertility; e.g., Rhizobium, Anabaena, Mycorrhiza.


️ Quick Revision (Before Exam)

  • Curd → Lactobacillus
  • Bread → Yeast
  • Cheese → Propionibacterium
  • Antibiotic → Penicillin
  • Acid → Citric (Aspergillus), Acetic (Acetobacter)
  • Immunosuppressant → Cyclosporin A
  • Cholesterol ↓ → Statins
  • Sewage → Methanogens
  • Biogas → Methanobacterium
  • Biopesticide → Bt toxin
  • Biofertiliser → Rhizobium, Anabaena, Mycorrhiza

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