🧬 Chapter 2: Human Reproduction – Class 12 MCQs | NCERT + NEET Focus

Rashmi Mishra
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🌸 Chapter 2

 Human Reproduction 

 (MCQs)


1.   Which of the following is not a part of the male reproductive system?
A. Testis
B. Vas deferens
C. Fallopian tube
D. Epididymis
Answer: C
Explanation: Fallopian tube belongs to the female reproductive system.


2.   Testes are located outside the abdominal cavity in the:
A. Scrotum
B. Penis
C. Urethra
D. Prostate gland
Answer: A
Explanation: The scrotum maintains temperature 2–2.5°C below body temperature for sperm formation.


3.   Functional unit of testis:
A. Seminiferous tubule
B. Epididymis
C. Vas deferens
D. Prostate gland
Answer: A
Explanation: Seminiferous tubules are the site of sperm production.


4.   Sertoli cells are found in:
A. Vas deferens
B. Seminiferous tubules
C. Prostate
D. Urethra
Answer: B
Explanation: Sertoli cells provide nourishment to developing sperms.


5.   Leydig cells secrete:
A. Progesterone
B. Testosterone
C. Estrogen
D. LH
Answer: B
Explanation: Leydig or interstitial cells secrete testosterone.


6.   Spermatogenesis occurs in:
A. Epididymis
B. Seminiferous tubules
C. Vas deferens
D. Urethra
Answer: B
Explanation: Spermatogenesis occurs in seminiferous tubules.


7.   Sperm maturation occurs in:
A. Vas deferens
B. Epididymis
C. Seminal vesicle
D. Urethra
Answer: B
Explanation: Epididymis stores and matures sperm.


8.   Which gland secretes fructose-rich fluid?
A. Seminal vesicle
B. Prostate
C. Bulbourethral gland
D. Cowper’s gland
Answer: A
Explanation: Seminal vesicle secretes fructose for sperm energy.


9.   The prostate gland secretion helps in:
A. Neutralizing vaginal acidity
B. Activating sperm
C. Enhancing motility
D. All of these
Answer: D
Explanation: Prostatic fluid neutralizes acidity and improves motility.


10.                   The total number of chromosomes in human sperm:
A. 23
B. 46
C. 44
D. 22
Answer: A
Explanation: Human sperm are haploid (n = 23).


11.                   Which part of sperm contains enzymes for fertilization?
A. Acrosome
B. Tail
C. Middle piece
D. Nucleus
Answer: A
Explanation: Acrosome has enzymes like hyaluronidase for egg penetration.


12.                   Mitochondria are present in which part of sperm?
A. Head
B. Middle piece
C. Tail
D. Acrosome
Answer: B
Explanation: Mitochondria in the middle piece supply energy for motility.


13.                   Hormone responsible for initiation of spermatogenesis:
A. LH
B. FSH
C. Testosterone
D. Both B and C
Answer: D
Explanation: FSH stimulates Sertoli cells and testosterone aids sperm production.


14.                   Semen is a mixture of:
A. Sperms and seminal plasma
B. Sperms only
C. Secretions of glands only
D. None
Answer: A
Explanation: Semen = sperm + secretions from accessory glands.


15.                   Vasectomy is a surgical method of birth control in which:
A. Vas deferens are cut
B. Fallopian tubes are tied
C. Penis is removed
D. None
Answer: A
Explanation: Vasectomy blocks sperm transport in males.



FEMALE REPRODUCTIVE SYSTEM


16.                   The female gonads are:
A. Testes
B. Ovaries
C. Uterus
D. Vagina
Answer: B
Explanation: Ovaries produce ova and female hormones.


17.                   Site of fertilization in human female:
A. Ampullary-isthmic junction
B. Uterus
C. Vagina
D. Cervix
Answer: A
Explanation: Fertilization occurs in the ampullary region of fallopian tube.


18.                   Finger-like projections at the end of fallopian tube are:
A. Fimbriae
B. Cilia
C. Villi
D. Follicles
Answer: A
Explanation: Fimbriae collect ovum after ovulation.


19.                   The uterus is also called:
A. Womb
B. Birth canal
C. Ovary
D. Cervix
Answer: A
Explanation: Embryo develops in the uterus (womb).


20.                   The innermost lining of uterus is:
A. Endometrium
B. Myometrium
C. Perimetrium
D. Epimetrium
Answer: A
Explanation: Endometrium thickens and sheds during menstruation.


21.                   The female copulatory organ is:
A. Vagina
B. Cervix
C. Uterus
D. Ovary
Answer: A
Explanation: Vagina receives the penis during copulation.


22.                   The part of ovary from which ovum is released:
A. Germinal epithelium
B. Graafian follicle
C. Corpus luteum
D. Follicular fluid
Answer: B
Explanation: Mature ovum is released from Graafian follicle.


23.                   The hormone responsible for ovulation:
A. FSH
B. LH
C. Estrogen
D. Progesterone
Answer: B
Explanation: LH surge triggers ovulation.


24.                   Corpus luteum secretes:
A. Estrogen
B. Progesterone
C. LH
D. FSH
Answer: B
Explanation: Progesterone maintains endometrium for implantation.


25.                   After fertilization, the corpus luteum remains active under the influence of:
A. FSH
B. hCG
C. LH
D. Oxytocin
Answer: B
Explanation: Human chorionic gonadotropin (hCG) maintains corpus luteum during pregnancy.


26.                   The term ‘menarche’ refers to:
A. First ovulation
B. First menstruation
C. Last menstruation
D. Pregnancy
Answer: B
Explanation: Menarche marks the onset of menstrual cycle at puberty.


27.                   ‘Menopause’ refers to:
A. Onset of puberty
B. Permanent cessation of menstruation
C. Temporary pause
D. None
Answer: B
Explanation: Menopause marks the end of reproductive phase.


28.                   Average duration of menstrual cycle:
A. 10 days
B. 14 days
C. 28 days
D. 35 days
Answer: C
Explanation: A typical menstrual cycle lasts 28 days.


29.                   The ovulation usually occurs on:
A. 1st day
B. 14th day
C. 28th day
D. 7th day
Answer: B
Explanation: Ovulation generally occurs mid-cycle (around day 14).


30.                   Which phase follows ovulation in menstrual cycle?
A. Follicular phase
B. Luteal phase
C. Menstrual phase
D. Proliferative phase
Answer: B
Explanation: Luteal phase is post-ovulatory and dominated by progesterone.



SPERMATOGENESIS & OOGENESIS


31.                   Spermatogonia are:
A. Diploid
B. Haploid
C. Triploid
D. Polyploid
Answer: A
Explanation: Spermatogonia (2n) undergo meiosis to form haploid sperms.


32.                   Primary spermatocyte divides to form:
A. Spermatid
B. Secondary spermatocyte
C. Spermatozoa
D. Spermatogonium
Answer: B
Explanation: Primary spermatocyte (2n) → two secondary spermatocytes (n).


33.                   Spermiogenesis is:
A. Formation of spermatid
B. Maturation of spermatid to sperm
C. Release of sperm
D. None
Answer: B
Explanation: Spermiogenesis is the final transformation of spermatids into spermatozoa.


34.                   Oogenesis starts:
A. At birth
B. Before birth
C. After puberty
D. After fertilization
Answer: B
Explanation: Oogenesis begins before birth, with primary oocytes formed in the fetal ovary.


35.                   At the time of birth, each ovum is arrested at:
A. Metaphase I
B. Prophase I
C. Metaphase II
D. Anaphase I
Answer: B
Explanation: Primary oocytes remain suspended in prophase I until puberty.


36.                   Ovulation releases:
A. Primary oocyte
B. Secondary oocyte
C. Oogonium
D. Ovum
Answer: B
Explanation: Secondary oocyte is released during ovulation and completes meiosis II only after fertilization.



FERTILIZATION & EMBRYO DEVELOPMENT


37.                   Site of fertilization in humans:
A. Ampulla of oviduct
B. Uterus
C. Cervix
D. Vagina
Answer: A
Explanation: Fertilization occurs in the ampullary-isthmic junction.


38.                   The acrosome reaction facilitates:
A. Sperm motility
B. Egg penetration
C. Egg activation
D. Cleavage
Answer: B
Explanation: Acrosomal enzymes digest zona pellucida for sperm entry.


39.                   The fertilized egg is called:
A. Embryo
B. Zygote
C. Morula
D. Blastula
Answer: B
Explanation: Fertilized ovum is the zygote (diploid).


40.                   Cleavage is a process of:
A. Growth
B. Cell division without growth
C. Fertilization
D. Meiosis
Answer: B
Explanation: Cleavage rapidly divides the zygote without increasing size.


41.                   Morula represents:
A. 8–16 cell stage
B. 32–64 cell stage
C. Blastocyst
D. Embryo
Answer: A
Explanation: Morula is an early solid mass of 8–16 cells.


42.                   Implantation occurs in:
A. Uterus
B. Fallopian tube
C. Ovary
D. Cervix
Answer: A
Explanation: Blastocyst embeds in endometrium of uterus.


43.                   Inner cell mass forms:
A. Embryo
B. Placenta
C. Chorion
D. Amnion
Answer: A
Explanation: Inner cell mass develops into embryo; trophoblast forms placenta.


44.                   The placenta is formed from:
A. Embryonic and maternal tissues
B. Only embryonic tissue
C. Only maternal tissue
D. None
Answer: A
Explanation: Placenta has both fetal (chorion) and maternal (endometrium) components.


45.                   Placenta acts as:
A. Endocrine gland
B. Transport organ
C. Respiratory organ
D. All of these
Answer: D
Explanation: Placenta exchanges gases, nutrients, and secretes hormones.


46.                   Which hormone is detected in pregnancy test?
A. LH
B. FSH
C. hCG
D. Estrogen
Answer: C
Explanation: hCG in urine is the basis for pregnancy tests.


47.                   Human gestation period is approximately:
A. 180 days
B. 240 days
C. 280 days
D. 300 days
Answer: C
Explanation: Human gestation lasts around 280 days (~9 months).


48.                   Parturition means:
A. Fertilization
B. Birth of baby
C. Lactation
D. Implantation
Answer: B
Explanation: Parturition = process of childbirth.


49.                   Which hormone stimulates uterine contraction during parturition?
A. Progesterone
B. Oxytocin
C. Relaxin
D. LH
Answer: B
Explanation: Oxytocin causes strong contractions during labor.


50.                   Which hormone softens the cervix during childbirth?
A. Relaxin
B. Estrogen
C. Progesterone
D. hCG
Answer: A
Explanation: Relaxin relaxes pelvic ligaments and cervix.



LACTATION & MATERNAL CARE


51.                   Mammary glands are modified:
A. Sweat glands
B. Sebaceous glands
C. Endocrine glands
D. None
Answer: A
Explanation: Mammary glands evolved from sweat glands.


52.                   First milk secreted after childbirth is:
A. Colostrum
B. Milk
C. Serum
D. Plasma
Answer: A
Explanation: Colostrum is rich in antibodies (IgA) for newborn immunity.


53.                   Hormone responsible for milk secretion:
A. Oxytocin
B. Prolactin
C. Estrogen
D. Progesterone
Answer: B
Explanation: Prolactin stimulates milk production.


54.                   Hormone for milk ejection (let-down reflex):
A. Oxytocin
B. FSH
C. LH
D. Estrogen
Answer: A
Explanation: Oxytocin helps milk flow from mammary glands.


55.                   Importance of breastfeeding:
A. Provides immunity
B. Provides nutrition
C. Strengthens bonding
D. All of these
Answer: D
Explanation: Breast milk gives nutrition, immunity, and emotional bonding.



REPRODUCTIVE HEALTH & CONTRACEPTION


56.                   Natural method of birth control:
A. Condom
B. Coitus interruptus
C. Oral pills
D. Copper-T
Answer: B
Explanation: Withdrawal method is natural but unreliable.


57.                   Barrier method example:
A. Condom
B. Oral pill
C. Vasectomy
D. Tubectomy
Answer: A
Explanation: Condoms prevent sperm entry into female tract.


58.                   Copper-T acts by:
A. Increasing sperm motility
B. Releasing copper ions toxic to sperms
C. Stimulating ovulation
D. None
Answer: B
Explanation: Copper ions suppress sperm motility and fertilization.


59.                   Surgical method in females:
A. Vasectomy
B. Tubectomy
C. Condom
D. Coitus interruptus
Answer: B
Explanation: Tubectomy blocks fallopian tubes.


60.                   Oral contraceptives mainly contain:
A. Estrogen and progesterone
B. FSH and LH
C. Testosterone
D. hCG
Answer: A
Explanation: These inhibit ovulation by feedback control.


61.                   Medical termination of pregnancy (MTP) is safest up to:
A. 12 weeks
B. 20 weeks
C. 30 weeks
D. 10 weeks
Answer: B
Explanation: Legal and safe up to 20 weeks.


62.                   STD caused by bacteria:
A. Syphilis
B. Genital herpes
C. AIDS
D. Hepatitis B
Answer: A
Explanation: Syphilis is caused by Treponema pallidum.


63.                   Virus causing AIDS:
A. HIV
B. HPV
C. HBV
D. HSV
Answer: A
Explanation: HIV attacks immune system (T-helper cells).


64.                   Common symptom of STDs:
A. Burning during urination
B. Discharge
C. Sores
D. All of these
Answer: D
Explanation: STDs show such symptoms.


65.                   Permanent method of contraception in males:
A. Vasectomy
B. Condom
C. Coitus interruptus
D. IUD
Answer: A
Explanation: Vasectomy cuts vas deferens.



FETAL DEVELOPMENT


66.                   Human embryo reaches uterus after:
A. 1 day
B. 2 days
C. 3–4 days
D. 7 days
Answer: C
Explanation: Zygote travels for 3–4 days before implantation.


67.                   Human chorionic gonadotropin is secreted by:
A. Placenta
B. Ovary
C. Pituitary
D. Uterus
Answer: A
Explanation: Placenta secretes hCG after implantation.


68.                   Which layer of embryo forms skin and nervous system?
A. Ectoderm
B. Endoderm
C. Mesoderm
D. None
Answer: A
Explanation: Ectoderm forms skin, brain, spinal cord.


69.                   Heart of human embryo starts beating at:
A. 1 week
B. 2 weeks
C. 3 weeks
D. 5 weeks
Answer: C
Explanation: Cardiac activity starts by 3rd week.


70.                   Which structure connects embryo to placenta?
A. Umbilical cord
B. Fallopian tube
C. Cervix
D. Amnion
Answer: A
Explanation: Umbilical cord transports nutrients and gases.


71. Which hormone is secreted by the corpus luteum?

A. Estrogen
B. Progesterone
C. LH
D. FSH
Answer: B
Explanation: The corpus luteum secretes progesterone, which maintains the endometrium for implantation and pregnancy.


72. The function of FSH in females is:

A. Ovulation
B. Follicle development
C. Maintenance of endometrium
D. Secretion of progesterone
Answer: B
Explanation: FSH (Follicle Stimulating Hormone) stimulates the growth and maturation of ovarian follicles.


73. LH surge in females is responsible for:

A. Follicle maturation
B. Ovulation
C. Corpus luteum degeneration
D. Estrogen secretion
Answer: B
Explanation: A sudden rise (surge) in LH mid-cycle (around day 14) causes ovulation.


74. Which hormone maintains pregnancy until the placenta forms?

A. Estrogen
B. FSH
C. Progesterone
D. Relaxin
Answer: C
Explanation: Progesterone maintains the uterine lining (endometrium) and prevents contractions during early pregnancy.


75. Human chorionic gonadotropin (hCG) is secreted by:

A. Ovary
B. Placenta
C. Corpus luteum
D. Pituitary gland
Answer: B
Explanation: hCG is secreted by the trophoblast cells of the placenta and supports the corpus luteum during early pregnancy.


76. Which hormone ensures milk ejection from mammary glands?

A. Estrogen
B. Oxytocin
C. Prolactin
D. Relaxin
Answer: B
Explanation: Oxytocin causes contraction of alveoli and ducts for milk ejection during lactation.


77. Which hormone promotes milk secretion after childbirth?

A. LH
B. FSH
C. Oxytocin
D. Prolactin
Answer: D
Explanation: Prolactin, secreted from the anterior pituitary, stimulates milk production in mammary glands.


78. Relaxin hormone facilitates:

A. Lactation
B. Relaxation of pelvic ligaments
C. Ovulation
D. Fertilization
Answer: B
Explanation: Relaxin, secreted during late pregnancy, relaxes pelvic ligaments and cervix to aid delivery.


79. Which of the following is NOT secreted by placenta?

A. hCG
B. hPL (human placental lactogen)
C. Relaxin
D. LH
Answer: D
Explanation: LH is secreted by the pituitary gland, not the placenta.


80. The hormone responsible for uterine contractions during labour is:

A. Oxytocin
B. Prolactin
C. Estrogen
D. Relaxin
Answer: A
Explanation: Oxytocin triggers strong uterine contractions during childbirth.


81. Which hormone acts as a signal for parturition?

A. hCG
B. Relaxin
C. Oxytocin
D. Estrogen
Answer: C
Explanation: Rising oxytocin levels initiate and intensify labour contractions.


82. Which hormone level falls drastically if pregnancy does not occur?

A. Estrogen and progesterone
B. LH and FSH
C. Oxytocin and relaxin
D. hCG and progesterone
Answer: A
Explanation: When fertilization doesn’t occur, progesterone and estrogen levels drop, leading to menstruation.


83. The primary cause of menstruation is:

A. Ovulation
B. Breakdown of endometrium
C. Fertilization
D. Formation of corpus luteum
Answer: B
Explanation: Due to lack of progesterone, the endometrium breaks down, causing menstrual bleeding.


84. Ovulation in a normal human female occurs around:

A. 7th day
B. 14th day
C. 21st day
D. 28th day
Answer: B
Explanation: Ovulation generally occurs on the 14th day of a 28-day menstrual cycle.


85. The pregnancy hormone detected in urine test kits is:

A. Estrogen
B. Progesterone
C. hCG
D. Oxytocin
Answer: C
Explanation: hCG (human chorionic gonadotropin) is detected in urine-based pregnancy tests.


86. Parturition refers to:

A. Fertilization
B. Embryo implantation
C. Delivery of baby
D. Formation of zygote
Answer: C
Explanation: Parturition is the process of childbirth.


87. Lactation refers to:

A. Ovulation
B. Milk production
C. Menstruation
D. Implantation
Answer: B
Explanation: Lactation is the production and secretion of milk from mammary glands after childbirth.


88. Which of the following is a temporary endocrine gland?

A. Pituitary
B. Thyroid
C. Corpus luteum
D. Adrenal
Answer: C
Explanation: Corpus luteum functions temporarily after ovulation, secreting progesterone.


89. Which structure is derived from the trophoblast of blastocyst?

A. Embryo
B. Placenta
C. Yolk sac
D. Amnion
Answer: B
Explanation: Trophoblast cells of blastocyst form the placenta.


90. The first milk secreted after childbirth is called:

A. Lactogen
B. Colostrum
C. Albumin
D. Prolactin
Answer: B
Explanation: Colostrum is rich in antibodies (IgA) and provides passive immunity to the newborn.


91. Which of the following is a male reproductive disorder?

A. Amenorrhea
B. Cryptorchidism
C. Dysmenorrhea
D. Endometriosis
Answer: B
Explanation: Cryptorchidism is the failure of testes to descend into the scrotum.


92. Infertility in females may be due to:

A. Blockage of fallopian tubes
B. Hormonal imbalance
C. Uterine disorders
D. All of the above
Answer: D
Explanation: Female infertility can be due to multiple reasons including tubal blockage, hormonal issues, or uterine defects.


93. Vasectomy involves cutting of:

A. Vas deferens
B. Urethra
C. Epididymis
D. Seminal vesicle
Answer: A
Explanation: Vasectomy is male sterilization involving cutting and sealing of vas deferens to prevent sperm transport.


94. Tubectomy involves cutting of:

A. Fallopian tubes
B. Ovaries
C. Uterus
D. Cervix
Answer: A
Explanation: Tubectomy (female sterilization) involves cutting of fallopian tubes to prevent fertilization.


95. Which of the following is a temporary contraceptive method?

A. Vasectomy
B. Tubectomy
C. Oral pills
D. Copper-T
Answer: C
Explanation: Oral pills are reversible and hence temporary.


96. Oral contraceptive pills prevent pregnancy by:

A. Destroying sperm
B. Preventing implantation
C. Inhibiting ovulation
D. Blocking oviducts
Answer: C
Explanation: Pills suppress LH and FSH, preventing ovulation.


97. Copper-T prevents pregnancy by:

A. Killing sperm
B. Preventing fertilization and implantation
C. Blocking fallopian tubes
D. Destroying ovum
Answer: B
Explanation: Copper ions released by the device affect sperm motility and prevent fertilization and implantation.


98. Which of the following diseases is NOT sexually transmitted?

A. AIDS
B. Syphilis
C. Hepatitis B
D. Tuberculosis
Answer: D
Explanation: Tuberculosis is airborne, not sexually transmitted.


99. The first case of AIDS was reported in:

A. 1950
B. 1965
C. 1981
D. 1990
Answer: C
Explanation: AIDS (Acquired Immunodeficiency Syndrome) was first reported in 1981 in the USA.


100. The causative agent of AIDS is:

A. HBV
B. HIV
C. HCV
D. HSV
Answer: B
Explanation: HIV (Human Immunodeficiency Virus) attacks the helper T-lymphocytes, weakening the immune system.

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