🧬 Chapter 2: Human Reproduction – Class 12 MCQs | NCERT + NEET Focus

Rashmi Mishra
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🌸 Chapter 2

 Human Reproduction 

 (MCQs)


1.   Which of the following is not a part of the male reproductive system?
A. Testis
B. Vas deferens
C. Fallopian tube
D. Epididymis
✅ Answer: C
Explanation: Fallopian tube belongs to the female reproductive system.


2.   Testes are located outside the abdominal cavity in the:
A. Scrotum
B. Penis
C. Urethra
D. Prostate gland
✅ Answer: A
Explanation: The scrotum maintains temperature 2–2.5°C below body temperature for sperm formation.


3.   Functional unit of testis:
A. Seminiferous tubule
B. Epididymis
C. Vas deferens
D. Prostate gland
✅ Answer: A
Explanation: Seminiferous tubules are the site of sperm production.


4.   Sertoli cells are found in:
A. Vas deferens
B. Seminiferous tubules
C. Prostate
D. Urethra
✅ Answer: B
Explanation: Sertoli cells provide nourishment to developing sperms.


5.   Leydig cells secrete:
A. Progesterone
B. Testosterone
C. Estrogen
D. LH
✅ Answer: B
Explanation: Leydig or interstitial cells secrete testosterone.


6.   Spermatogenesis occurs in:
A. Epididymis
B. Seminiferous tubules
C. Vas deferens
D. Urethra
✅ Answer: B
Explanation: Spermatogenesis occurs in seminiferous tubules.


7.   Sperm maturation occurs in:
A. Vas deferens
B. Epididymis
C. Seminal vesicle
D. Urethra
✅ Answer: B
Explanation: Epididymis stores and matures sperm.


8.   Which gland secretes fructose-rich fluid?
A. Seminal vesicle
B. Prostate
C. Bulbourethral gland
D. Cowper’s gland
✅ Answer: A
Explanation: Seminal vesicle secretes fructose for sperm energy.


9.   The prostate gland secretion helps in:
A. Neutralizing vaginal acidity
B. Activating sperm
C. Enhancing motility
D. All of these
✅ Answer: D
Explanation: Prostatic fluid neutralizes acidity and improves motility.


10.                   The total number of chromosomes in human sperm:
A. 23
B. 46
C. 44
D. 22
✅ Answer: A
Explanation: Human sperm are haploid (n = 23).


11.                   Which part of sperm contains enzymes for fertilization?
A. Acrosome
B. Tail
C. Middle piece
D. Nucleus
✅ Answer: A
Explanation: Acrosome has enzymes like hyaluronidase for egg penetration.


12.                   Mitochondria are present in which part of sperm?
A. Head
B. Middle piece
C. Tail
D. Acrosome
✅ Answer: B
Explanation: Mitochondria in the middle piece supply energy for motility.


13.                   Hormone responsible for initiation of spermatogenesis:
A. LH
B. FSH
C. Testosterone
D. Both B and C
✅ Answer: D
Explanation: FSH stimulates Sertoli cells and testosterone aids sperm production.


14.                   Semen is a mixture of:
A. Sperms and seminal plasma
B. Sperms only
C. Secretions of glands only
D. None
✅ Answer: A
Explanation: Semen = sperm + secretions from accessory glands.


15.                   Vasectomy is a surgical method of birth control in which:
A. Vas deferens are cut
B. Fallopian tubes are tied
C. Penis is removed
D. None
✅ Answer: A
Explanation: Vasectomy blocks sperm transport in males.



FEMALE REPRODUCTIVE SYSTEM


16.                   The female gonads are:
A. Testes
B. Ovaries
C. Uterus
D. Vagina
✅ Answer: B
Explanation: Ovaries produce ova and female hormones.


17.                   Site of fertilization in human female:
A. Ampullary-isthmic junction
B. Uterus
C. Vagina
D. Cervix
✅ Answer: A
Explanation: Fertilization occurs in the ampullary region of fallopian tube.


18.                   Finger-like projections at the end of fallopian tube are:
A. Fimbriae
B. Cilia
C. Villi
D. Follicles
✅ Answer: A
Explanation: Fimbriae collect ovum after ovulation.


19.                   The uterus is also called:
A. Womb
B. Birth canal
C. Ovary
D. Cervix
✅ Answer: A
Explanation: Embryo develops in the uterus (womb).


20.                   The innermost lining of uterus is:
A. Endometrium
B. Myometrium
C. Perimetrium
D. Epimetrium
✅ Answer: A
Explanation: Endometrium thickens and sheds during menstruation.


21.                   The female copulatory organ is:
A. Vagina
B. Cervix
C. Uterus
D. Ovary
✅ Answer: A
Explanation: Vagina receives the penis during copulation.


22.                   The part of ovary from which ovum is released:
A. Germinal epithelium
B. Graafian follicle
C. Corpus luteum
D. Follicular fluid
✅ Answer: B
Explanation: Mature ovum is released from Graafian follicle.


23.                   The hormone responsible for ovulation:
A. FSH
B. LH
C. Estrogen
D. Progesterone
✅ Answer: B
Explanation: LH surge triggers ovulation.


24.                   Corpus luteum secretes:
A. Estrogen
B. Progesterone
C. LH
D. FSH
✅ Answer: B
Explanation: Progesterone maintains endometrium for implantation.


25.                   After fertilization, the corpus luteum remains active under the influence of:
A. FSH
B. hCG
C. LH
D. Oxytocin
✅ Answer: B
Explanation: Human chorionic gonadotropin (hCG) maintains corpus luteum during pregnancy.


26.                   The term ‘menarche’ refers to:
A. First ovulation
B. First menstruation
C. Last menstruation
D. Pregnancy
✅ Answer: B
Explanation: Menarche marks the onset of menstrual cycle at puberty.


27.                   ‘Menopause’ refers to:
A. Onset of puberty
B. Permanent cessation of menstruation
C. Temporary pause
D. None
✅ Answer: B
Explanation: Menopause marks the end of reproductive phase.


28.                   Average duration of menstrual cycle:
A. 10 days
B. 14 days
C. 28 days
D. 35 days
✅ Answer: C
Explanation: A typical menstrual cycle lasts 28 days.


29.                   The ovulation usually occurs on:
A. 1st day
B. 14th day
C. 28th day
D. 7th day
✅ Answer: B
Explanation: Ovulation generally occurs mid-cycle (around day 14).


30.                   Which phase follows ovulation in menstrual cycle?
A. Follicular phase
B. Luteal phase
C. Menstrual phase
D. Proliferative phase
✅ Answer: B
Explanation: Luteal phase is post-ovulatory and dominated by progesterone.



SPERMATOGENESIS & OOGENESIS


31.                   Spermatogonia are:
A. Diploid
B. Haploid
C. Triploid
D. Polyploid
✅ Answer: A
Explanation: Spermatogonia (2n) undergo meiosis to form haploid sperms.


32.                   Primary spermatocyte divides to form:
A. Spermatid
B. Secondary spermatocyte
C. Spermatozoa
D. Spermatogonium
✅ Answer: B
Explanation: Primary spermatocyte (2n) → two secondary spermatocytes (n).


33.                   Spermiogenesis is:
A. Formation of spermatid
B. Maturation of spermatid to sperm
C. Release of sperm
D. None
✅ Answer: B
Explanation: Spermiogenesis is the final transformation of spermatids into spermatozoa.


34.                   Oogenesis starts:
A. At birth
B. Before birth
C. After puberty
D. After fertilization
✅ Answer: B
Explanation: Oogenesis begins before birth, with primary oocytes formed in the fetal ovary.


35.                   At the time of birth, each ovum is arrested at:
A. Metaphase I
B. Prophase I
C. Metaphase II
D. Anaphase I
✅ Answer: B
Explanation: Primary oocytes remain suspended in prophase I until puberty.


36.                   Ovulation releases:
A. Primary oocyte
B. Secondary oocyte
C. Oogonium
D. Ovum
✅ Answer: B
Explanation: Secondary oocyte is released during ovulation and completes meiosis II only after fertilization.



FERTILIZATION & EMBRYO DEVELOPMENT


37.                   Site of fertilization in humans:
A. Ampulla of oviduct
B. Uterus
C. Cervix
D. Vagina
✅ Answer: A
Explanation: Fertilization occurs in the ampullary-isthmic junction.


38.                   The acrosome reaction facilitates:
A. Sperm motility
B. Egg penetration
C. Egg activation
D. Cleavage
✅ Answer: B
Explanation: Acrosomal enzymes digest zona pellucida for sperm entry.


39.                   The fertilized egg is called:
A. Embryo
B. Zygote
C. Morula
D. Blastula
✅ Answer: B
Explanation: Fertilized ovum is the zygote (diploid).


40.                   Cleavage is a process of:
A. Growth
B. Cell division without growth
C. Fertilization
D. Meiosis
✅ Answer: B
Explanation: Cleavage rapidly divides the zygote without increasing size.


41.                   Morula represents:
A. 8–16 cell stage
B. 32–64 cell stage
C. Blastocyst
D. Embryo
✅ Answer: A
Explanation: Morula is an early solid mass of 8–16 cells.


42.                   Implantation occurs in:
A. Uterus
B. Fallopian tube
C. Ovary
D. Cervix
✅ Answer: A
Explanation: Blastocyst embeds in endometrium of uterus.


43.                   Inner cell mass forms:
A. Embryo
B. Placenta
C. Chorion
D. Amnion
✅ Answer: A
Explanation: Inner cell mass develops into embryo; trophoblast forms placenta.


44.                   The placenta is formed from:
A. Embryonic and maternal tissues
B. Only embryonic tissue
C. Only maternal tissue
D. None
✅ Answer: A
Explanation: Placenta has both fetal (chorion) and maternal (endometrium) components.


45.                   Placenta acts as:
A. Endocrine gland
B. Transport organ
C. Respiratory organ
D. All of these
✅ Answer: D
Explanation: Placenta exchanges gases, nutrients, and secretes hormones.


46.                   Which hormone is detected in pregnancy test?
A. LH
B. FSH
C. hCG
D. Estrogen
✅ Answer: C
Explanation: hCG in urine is the basis for pregnancy tests.


47.                   Human gestation period is approximately:
A. 180 days
B. 240 days
C. 280 days
D. 300 days
✅ Answer: C
Explanation: Human gestation lasts around 280 days (~9 months).


48.                   Parturition means:
A. Fertilization
B. Birth of baby
C. Lactation
D. Implantation
✅ Answer: B
Explanation: Parturition = process of childbirth.


49.                   Which hormone stimulates uterine contraction during parturition?
A. Progesterone
B. Oxytocin
C. Relaxin
D. LH
✅ Answer: B
Explanation: Oxytocin causes strong contractions during labor.


50.                   Which hormone softens the cervix during childbirth?
A. Relaxin
B. Estrogen
C. Progesterone
D. hCG
✅ Answer: A
Explanation: Relaxin relaxes pelvic ligaments and cervix.



LACTATION & MATERNAL CARE


51.                   Mammary glands are modified:
A. Sweat glands
B. Sebaceous glands
C. Endocrine glands
D. None
✅ Answer: A
Explanation: Mammary glands evolved from sweat glands.


52.                   First milk secreted after childbirth is:
A. Colostrum
B. Milk
C. Serum
D. Plasma
✅ Answer: A
Explanation: Colostrum is rich in antibodies (IgA) for newborn immunity.


53.                   Hormone responsible for milk secretion:
A. Oxytocin
B. Prolactin
C. Estrogen
D. Progesterone
✅ Answer: B
Explanation: Prolactin stimulates milk production.


54.                   Hormone for milk ejection (let-down reflex):
A. Oxytocin
B. FSH
C. LH
D. Estrogen
✅ Answer: A
Explanation: Oxytocin helps milk flow from mammary glands.


55.                   Importance of breastfeeding:
A. Provides immunity
B. Provides nutrition
C. Strengthens bonding
D. All of these
✅ Answer: D
Explanation: Breast milk gives nutrition, immunity, and emotional bonding.



REPRODUCTIVE HEALTH & CONTRACEPTION


56.                   Natural method of birth control:
A. Condom
B. Coitus interruptus
C. Oral pills
D. Copper-T
✅ Answer: B
Explanation: Withdrawal method is natural but unreliable.


57.                   Barrier method example:
A. Condom
B. Oral pill
C. Vasectomy
D. Tubectomy
✅ Answer: A
Explanation: Condoms prevent sperm entry into female tract.


58.                   Copper-T acts by:
A. Increasing sperm motility
B. Releasing copper ions toxic to sperms
C. Stimulating ovulation
D. None
✅ Answer: B
Explanation: Copper ions suppress sperm motility and fertilization.


59.                   Surgical method in females:
A. Vasectomy
B. Tubectomy
C. Condom
D. Coitus interruptus
✅ Answer: B
Explanation: Tubectomy blocks fallopian tubes.


60.                   Oral contraceptives mainly contain:
A. Estrogen and progesterone
B. FSH and LH
C. Testosterone
D. hCG
✅ Answer: A
Explanation: These inhibit ovulation by feedback control.


61.                   Medical termination of pregnancy (MTP) is safest up to:
A. 12 weeks
B. 20 weeks
C. 30 weeks
D. 10 weeks
✅ Answer: B
Explanation: Legal and safe up to 20 weeks.


62.                   STD caused by bacteria:
A. Syphilis
B. Genital herpes
C. AIDS
D. Hepatitis B
✅ Answer: A
Explanation: Syphilis is caused by Treponema pallidum.


63.                   Virus causing AIDS:
A. HIV
B. HPV
C. HBV
D. HSV
✅ Answer: A
Explanation: HIV attacks immune system (T-helper cells).


64.                   Common symptom of STDs:
A. Burning during urination
B. Discharge
C. Sores
D. All of these
✅ Answer: D
Explanation: STDs show such symptoms.


65.                   Permanent method of contraception in males:
A. Vasectomy
B. Condom
C. Coitus interruptus
D. IUD
✅ Answer: A
Explanation: Vasectomy cuts vas deferens.



FETAL DEVELOPMENT


66.                   Human embryo reaches uterus after:
A. 1 day
B. 2 days
C. 3–4 days
D. 7 days
✅ Answer: C
Explanation: Zygote travels for 3–4 days before implantation.


67.                   Human chorionic gonadotropin is secreted by:
A. Placenta
B. Ovary
C. Pituitary
D. Uterus
✅ Answer: A
Explanation: Placenta secretes hCG after implantation.


68.                   Which layer of embryo forms skin and nervous system?
A. Ectoderm
B. Endoderm
C. Mesoderm
D. None
✅ Answer: A
Explanation: Ectoderm forms skin, brain, spinal cord.


69.                   Heart of human embryo starts beating at:
A. 1 week
B. 2 weeks
C. 3 weeks
D. 5 weeks
✅ Answer: C
Explanation: Cardiac activity starts by 3rd week.


70.                   Which structure connects embryo to placenta?
A. Umbilical cord
B. Fallopian tube
C. Cervix
D. Amnion
✅ Answer: A
Explanation: Umbilical cord transports nutrients and gases.


71. Which hormone is secreted by the corpus luteum?

A. Estrogen
B. Progesterone
C. LH
D. FSH
✅ Answer: B
Explanation: The corpus luteum secretes progesterone, which maintains the endometrium for implantation and pregnancy.


72. The function of FSH in females is:

A. Ovulation
B. Follicle development
C. Maintenance of endometrium
D. Secretion of progesterone
✅ Answer: B
Explanation: FSH (Follicle Stimulating Hormone) stimulates the growth and maturation of ovarian follicles.


73. LH surge in females is responsible for:

A. Follicle maturation
B. Ovulation
C. Corpus luteum degeneration
D. Estrogen secretion
✅ Answer: B
Explanation: A sudden rise (surge) in LH mid-cycle (around day 14) causes ovulation.


74. Which hormone maintains pregnancy until the placenta forms?

A. Estrogen
B. FSH
C. Progesterone
D. Relaxin
✅ Answer: C
Explanation: Progesterone maintains the uterine lining (endometrium) and prevents contractions during early pregnancy.


75. Human chorionic gonadotropin (hCG) is secreted by:

A. Ovary
B. Placenta
C. Corpus luteum
D. Pituitary gland
✅ Answer: B
Explanation: hCG is secreted by the trophoblast cells of the placenta and supports the corpus luteum during early pregnancy.


76. Which hormone ensures milk ejection from mammary glands?

A. Estrogen
B. Oxytocin
C. Prolactin
D. Relaxin
✅ Answer: B
Explanation: Oxytocin causes contraction of alveoli and ducts for milk ejection during lactation.


77. Which hormone promotes milk secretion after childbirth?

A. LH
B. FSH
C. Oxytocin
D. Prolactin
✅ Answer: D
Explanation: Prolactin, secreted from the anterior pituitary, stimulates milk production in mammary glands.


78. Relaxin hormone facilitates:

A. Lactation
B. Relaxation of pelvic ligaments
C. Ovulation
D. Fertilization
✅ Answer: B
Explanation: Relaxin, secreted during late pregnancy, relaxes pelvic ligaments and cervix to aid delivery.


79. Which of the following is NOT secreted by placenta?

A. hCG
B. hPL (human placental lactogen)
C. Relaxin
D. LH
✅ Answer: D
Explanation: LH is secreted by the pituitary gland, not the placenta.


80. The hormone responsible for uterine contractions during labour is:

A. Oxytocin
B. Prolactin
C. Estrogen
D. Relaxin
✅ Answer: A
Explanation: Oxytocin triggers strong uterine contractions during childbirth.


81. Which hormone acts as a signal for parturition?

A. hCG
B. Relaxin
C. Oxytocin
D. Estrogen
✅ Answer: C
Explanation: Rising oxytocin levels initiate and intensify labour contractions.


82. Which hormone level falls drastically if pregnancy does not occur?

A. Estrogen and progesterone
B. LH and FSH
C. Oxytocin and relaxin
D. hCG and progesterone
✅ Answer: A
Explanation: When fertilization doesn’t occur, progesterone and estrogen levels drop, leading to menstruation.


83. The primary cause of menstruation is:

A. Ovulation
B. Breakdown of endometrium
C. Fertilization
D. Formation of corpus luteum
✅ Answer: B
Explanation: Due to lack of progesterone, the endometrium breaks down, causing menstrual bleeding.


84. Ovulation in a normal human female occurs around:

A. 7th day
B. 14th day
C. 21st day
D. 28th day
✅ Answer: B
Explanation: Ovulation generally occurs on the 14th day of a 28-day menstrual cycle.


85. The pregnancy hormone detected in urine test kits is:

A. Estrogen
B. Progesterone
C. hCG
D. Oxytocin
✅ Answer: C
Explanation: hCG (human chorionic gonadotropin) is detected in urine-based pregnancy tests.


86. Parturition refers to:

A. Fertilization
B. Embryo implantation
C. Delivery of baby
D. Formation of zygote
✅ Answer: C
Explanation: Parturition is the process of childbirth.


87. Lactation refers to:

A. Ovulation
B. Milk production
C. Menstruation
D. Implantation
✅ Answer: B
Explanation: Lactation is the production and secretion of milk from mammary glands after childbirth.


88. Which of the following is a temporary endocrine gland?

A. Pituitary
B. Thyroid
C. Corpus luteum
D. Adrenal
✅ Answer: C
Explanation: Corpus luteum functions temporarily after ovulation, secreting progesterone.


89. Which structure is derived from the trophoblast of blastocyst?

A. Embryo
B. Placenta
C. Yolk sac
D. Amnion
✅ Answer: B
Explanation: Trophoblast cells of blastocyst form the placenta.


90. The first milk secreted after childbirth is called:

A. Lactogen
B. Colostrum
C. Albumin
D. Prolactin
✅ Answer: B
Explanation: Colostrum is rich in antibodies (IgA) and provides passive immunity to the newborn.


91. Which of the following is a male reproductive disorder?

A. Amenorrhea
B. Cryptorchidism
C. Dysmenorrhea
D. Endometriosis
✅ Answer: B
Explanation: Cryptorchidism is the failure of testes to descend into the scrotum.


92. Infertility in females may be due to:

A. Blockage of fallopian tubes
B. Hormonal imbalance
C. Uterine disorders
D. All of the above
✅ Answer: D
Explanation: Female infertility can be due to multiple reasons including tubal blockage, hormonal issues, or uterine defects.


93. Vasectomy involves cutting of:

A. Vas deferens
B. Urethra
C. Epididymis
D. Seminal vesicle
✅ Answer: A
Explanation: Vasectomy is male sterilization involving cutting and sealing of vas deferens to prevent sperm transport.


94. Tubectomy involves cutting of:

A. Fallopian tubes
B. Ovaries
C. Uterus
D. Cervix
✅ Answer: A
Explanation: Tubectomy (female sterilization) involves cutting of fallopian tubes to prevent fertilization.


95. Which of the following is a temporary contraceptive method?

A. Vasectomy
B. Tubectomy
C. Oral pills
D. Copper-T
✅ Answer: C
Explanation: Oral pills are reversible and hence temporary.


96. Oral contraceptive pills prevent pregnancy by:

A. Destroying sperm
B. Preventing implantation
C. Inhibiting ovulation
D. Blocking oviducts
✅ Answer: C
Explanation: Pills suppress LH and FSH, preventing ovulation.


97. Copper-T prevents pregnancy by:

A. Killing sperm
B. Preventing fertilization and implantation
C. Blocking fallopian tubes
D. Destroying ovum
✅ Answer: B
Explanation: Copper ions released by the device affect sperm motility and prevent fertilization and implantation.


98. Which of the following diseases is NOT sexually transmitted?

A. AIDS
B. Syphilis
C. Hepatitis B
D. Tuberculosis
✅ Answer: D
Explanation: Tuberculosis is airborne, not sexually transmitted.


99. The first case of AIDS was reported in:

A. 1950
B. 1965
C. 1981
D. 1990
✅ Answer: C
Explanation: AIDS (Acquired Immunodeficiency Syndrome) was first reported in 1981 in the USA.


100. The causative agent of AIDS is:

A. HBV
B. HIV
C. HCV
D. HSV
✅ Answer: B
Explanation: HIV (Human Immunodeficiency Virus) attacks the helper T-lymphocytes, weakening the immune system.

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