🧬 Chapter 2: Human Reproduction — 5 Marks Questions with Answers | NCERT + NEET Focus

Rashmi Mishra
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🌸 Chapter 2

 Human Reproduction 

(5 Marks )

🌸 Human Reproduction – 5 Marks Questions with Answers


1. Describe the structure and function of the male reproductive system.

Answer:

  • Primary sex organ: Testes – produce sperm and testosterone.
  • Accessory ducts: Epididymis, vas deferens, ejaculatory duct, and urethra – transport and mature sperm.
  • Glands: Seminal vesicles (secrete fructose), prostate (milky fluid), and bulbourethral glands (lubrication).
  • External genitalia: Penis – delivers sperm; scrotum – maintains testicular temperature.
    Function: Together, they produce, mature, and deliver sperm for fertilization.

2. Describe the structure and function of the female reproductive system.

Answer:

  • Ovaries: Produce ova and hormones (estrogen and progesterone).
  • Fallopian tubes: Transport ova; site of fertilization.
  • Uterus: Site of implantation and fetal development.
  • Cervix & vagina: Facilitate sperm entry and childbirth.
    Function: Production of ova, fertilization, and nurturing of embryo.

3. Explain the structure of a mature human sperm.

Answer:

  • Head: Contains haploid nucleus and acrosome (with enzymes for egg penetration).
  • Neck: Contains centrioles.
  • Middle piece: Mitochondria for energy.
  • Tail: Flagellum for motility.
    Function: To deliver male genetic material to the ovum.

4. Explain the structure of a human ovum.

Answer:

  • Spherical cell, non-motile, surrounded by zona pellucida and corona radiata.
  • Contains haploid nucleus and cytoplasm rich in nutrients.
    Function: Carries female genetic material and supports early zygote formation.

5. Explain the process of spermatogenesis.

Answer:

  • Occurs in seminiferous tubules.
  • SpermatogoniaPrimary spermatocyteSecondary spermatocyteSpermatidSpermatozoa.
  • Sertoli cells provide nourishment; Leydig cells secrete testosterone.
    Function: Production of haploid, motile sperms.

6. Explain the process of oogenesis.

Answer:

  • Begins before birth: oogonia → primary oocytes (arrested in prophase I).
  • After puberty: primary oocyte completes meiosis I → secondary oocyte + polar body.
  • After fertilization: meiosis II completes to form ovum and second polar body.
    Result: One ovum and three polar bodies are formed.

7. Describe the role of hormones in the menstrual cycle.

Answer:

  • FSH: Stimulates follicle growth.
  • LH: Triggers ovulation and corpus luteum formation.
  • Estrogen: Rebuilds endometrium.
  • Progesterone: Maintains endometrium.
    Cycle: Follicular → Ovulation → Luteal → Menstrual phase.

8. Explain the phases of the menstrual cycle.

Answer:

1.   Menstrual Phase (1–5 days): Shedding of endometrium.

2.   Follicular Phase (6–14): Follicle growth, estrogen rise.

3.   Ovulation (14th day): LH surge releases egg.

4.   Luteal Phase (15–28): Corpus luteum secretes progesterone.
If no fertilization, cycle repeats.


9. Explain the process of fertilization in humans.

Answer:

  • Occurs in ampulla of fallopian tube.
  • Sperm penetrates corona radiata and zona pellucida.
  • Acrosomal reaction releases enzymes.
  • Sperm and egg nuclei fuse → zygote (diploid).
    Significance: Restores diploid chromosome number.

10. Describe the process of implantation.

Answer:

  • Zygote divides to form blastocyst.
  • Reaches uterus after 5–7 days.
  • Blastocyst attaches to endometrium (implantation).
  • Trophoblast cells secrete enzymes for embedding.
    Result: Establishment of pregnancy.

11. Describe the stages of embryonic development up to gastrulation.

Answer:

  • Cleavage: Zygote → 2, 4, 8, 16 cells → Morula.
  • Blastulation: Morula → Blastocyst.
  • Implantation: Blastocyst embeds in uterine wall.
  • Gastrulation: Formation of three germ layers (ectoderm, mesoderm, endoderm).

12. What is placenta? Describe its functions.

Answer:

  • Placenta forms from chorionic villi and maternal tissue.
    Functions:

1.   Exchange of gases and nutrients.

2.   Removes fetal waste.

3.   Secretes hormones: hCG, estrogen, progesterone, hPL.

4.   Provides immunity.

5.   Acts as barrier to some harmful substances.


13. Describe the role of hormones during pregnancy.

Answer:

  • hCG: Maintains corpus luteum.
  • Progesterone & Estrogen: Maintain endometrium, inhibit ovulation.
  • hPL: Promotes fetal growth and maternal metabolism.
  • Relaxin: Softens pelvic ligaments for childbirth.

14. Explain the process of parturition.

Answer:

  • Triggered by fetal ejection reflex.
  • Oxytocin released → uterine contractions.
  • Positive feedback between contractions and oxytocin.
    Stages: Dilation → Expulsion → Placental stage.

15. Explain lactation and colostrum.

Answer:

  • Lactation: Milk secretion by mammary glands post-childbirth.
  • Stimulated by prolactin; oxytocin aids ejection.
  • Colostrum: First yellowish milk, rich in antibodies – boosts infant immunity.

16. Explain the role of testes in reproduction.

Answer:

  • Produce sperm (exocrine function).
  • Secrete testosterone (endocrine function).
    Testosterone: Controls spermatogenesis, muscle growth, and secondary sexual characters.

17. Explain the role of ovary in reproduction.

Answer:

  • Produces ova and hormones.
  • Estrogen: Controls female secondary characters and endometrial growth.
  • Progesterone: Maintains pregnancy.

18. What is the importance of acrosomal reaction during fertilization?

Answer:

  • Acrosome releases enzymes like hyaluronidase and acrosin.
  • Helps sperm penetrate zona pellucida.
  • Ensures species-specific fertilization.

19. Explain gametogenesis and its types.

Answer:

  • Formation of gametes (haploid cells) from germ cells.
  • Spermatogenesis: In males; produces sperms.
  • Oogenesis: In females; produces ovum.
    Importance: Maintains chromosome number in species.

20. Explain hormonal control of spermatogenesis.

Answer:

  • GnRH (from hypothalamus): Stimulates pituitary.
  • FSH: Acts on Sertoli cells → spermatogenesis.
  • LH: Stimulates Leydig cells → testosterone.
  • Testosterone: Promotes sperm maturation.

(… continuing in same pattern …)


Would you like me to continue from Question 21 to 50 (remaining 5-mark questions covering implantation, pregnancy hormones, menstrual cycle disorders, IVF, test-tube baby, twins, contraception, and NEET-based conceptual topics)?
It’ll include both Board-style and NEET-integrated 5-mark answers.

You said:

(… continuing in same pattern …)

ChatGPT said:

Perfect 👍 Here’s the continuation (Questions 21–50) of 5-mark questions with answers from Chapter – Human Reproduction (Class 12 Biology, NCERT-based) — detailed for both CBSE Board and NEET preparation.


🌸 Human Reproduction – 5 Marks Questions (21–50)


21. Describe the process of implantation and its significance.

Answer:

  • Implantation is the attachment of the blastocyst to the uterine wall about 6–7 days after fertilization.
  • Process:

1.   Trophoblast cells of the blastocyst secrete enzymes to erode uterine epithelium.

2.   Blastocyst embeds into endometrium.

3.   Trophoblast differentiates into cytotrophoblast and syncytiotrophoblast.

  • Significance:

o   Establishes connection between mother and embryo.

o   Leads to formation of the placenta.

o   Marks beginning of pregnancy.


22. Explain the structure, development, and functions of placenta.

Answer:

  • Structure: Formed from chorionic villi (fetal part) and uterine tissue (maternal part).
  • Functions:

1.   Exchange of nutrients and gases.

2.   Removal of fetal waste.

3.   Secretion of hormones – hCG, hPL, progesterone, estrogen.

4.   Acts as barrier to harmful substances.

5.   Provides passive immunity via maternal antibodies.

  • Development: Begins after implantation; fully formed by 12 weeks.

23. Describe the hormonal control of the menstrual cycle.

Answer:

  • FSH: Stimulates follicle growth.
  • Estrogen: Rebuilds endometrium.
  • LH: Surge causes ovulation.
  • Progesterone: Maintains endometrium post-ovulation.
  • If fertilization fails → progesterone & estrogen drop → menstruation occurs.
  • Hormones are regulated by hypothalamus (GnRH)pituitaryovaries feedback loop.

24. Explain the role of different glands associated with male reproductive system.

Answer:

  • Seminal vesicles: Secrete fructose (energy source) and prostaglandins.
  • Prostate gland: Adds milky fluid with enzymes and calcium ions.
  • Bulbourethral (Cowper’s) glands: Secrete mucus for lubrication and neutralization of urine residues.
    Function: Secretions together form seminal plasma, enhancing sperm motility and fertility.

25. Describe the process of fertilization and its physiological significance.

Answer:

  • Fertilization: Union of sperm and ovum in ampulla of fallopian tube.
  • Steps:

1.   Sperm capacitation.

2.   Acrosomal reaction.

3.   Fusion of gamete membranes.

4.   Completion of meiosis II in ovum.

5.   Formation of diploid zygote.

  • Significance: Restores chromosome number and initiates embryo formation.

26. Explain the hormonal changes during pregnancy.

Answer:

  • hCG: Maintains corpus luteum.
  • Progesterone: Maintains endometrium, prevents contractions.
  • Estrogen: Promotes uterine growth and breast development.
  • hPL: Regulates maternal metabolism.
  • Relaxin: Softens cervix for childbirth.
    Combined effect: Ensure fetal development and preparation for parturition.

27. Describe the events of parturition (childbirth).

Answer:

1.   Fetal ejection reflex stimulates oxytocin release.

2.   Oxytocin induces uterine contractions.

3.   Positive feedback loop increases contraction intensity.

4.   Three stages:

o   Dilation stage – cervix opens.

o   Expulsion stage – baby delivered.

o   Afterbirth stage – placenta expelled.
Result: Delivery of baby and placenta safely.


28. Explain the process of lactation and the importance of colostrum.

Answer:

  • Lactation: Milk production by mammary glands under prolactin and oxytocin.
  • Colostrum: Yellowish first milk, rich in antibodies (IgA) and nutrients.
    Importance: Provides passive immunity and nutrition to newborn.

29. Explain gametogenesis with suitable diagrams.

Answer:

  • Spermatogenesis: Formation of haploid sperms from spermatogonia.
  • Oogenesis: Formation of haploid ovum from oogonia.
    Differences: Spermatogenesis produces 4 functional sperms; oogenesis produces 1 ovum and 3 polar bodies.
    Importance: Maintains species’ chromosome number.

30. Describe the process of embryo development up to blastocyst formation.

Answer:

  • Zygote divides by cleavage → 2, 4, 8, 16-cell stagesMorulaBlastocyst.
  • Blastocyst: Outer trophoblast, inner cell mass, and fluid-filled cavity.
  • Travels to uterus for implantation.
    Importance: Prepares for placental attachment and further differentiation.

31. What are the major events of the menstrual cycle? Describe each.

Answer:

1.   Menstrual phase: Shedding of uterine lining.

2.   Follicular phase: Follicle growth, estrogen secretion.

3.   Ovulatory phase: LH surge, ovum release.

4.   Luteal phase: Corpus luteum secretes progesterone.
Cycle repeats if fertilization does not occur.


32. Compare spermatogenesis and oogenesis.

Answer:

Feature

Spermatogenesis

Oogenesis

Site

Testes

Ovaries

Start

Puberty

Before birth

End

Continuous

Menopause

Product

4 sperms

1 ovum + 3 polar bodies

Duration

Continuous

Cyclic

Result: Both form haploid gametes essential for fertilization.


33. Describe the structure and function of a seminiferous tubule.

Answer:

  • Structure: Lined by germinal epithelium with spermatogenic and Sertoli cells.
  • Interstitial (Leydig) cells lie between tubules.
  • Function:
    • Site of sperm production.
    • Sertoli cells nourish developing sperms.
    • Leydig cells secrete testosterone.

34. What is the role of corpus luteum in female reproductive physiology?

Answer:

  • Formed from ruptured follicle after ovulation.
  • Secretes progesterone and some estrogen.
  • Maintains endometrium for implantation.
  • Degenerates into corpus albicans if fertilization fails.
    Importance: Ensures continuation or termination of menstrual cycle.

35. Explain the hormonal regulation of male reproductive functions.

Answer:

  • GnRH (Hypothalamus): Stimulates pituitary.
  • FSH: Acts on Sertoli cells → spermatogenesis.
  • LH: Stimulates Leydig cells → testosterone secretion.
  • Testosterone: Maintains libido, secondary sex characters, sperm production.
  • Negative feedback via testosterone inhibits GnRH and LH.

36. Explain the stages of embryonic development in humans.

Answer:

  • Zygote → Cleavage → Morula → Blastocyst → Implantation → Gastrulation → Organogenesis.
  • Embryo develops 3 germ layers: ectoderm, mesoderm, endoderm.
    Result: Formation of tissues and organs of the fetus.

37. How is pregnancy detected in women?

Answer:

  • Test: Detection of hCG (human chorionic gonadotropin) in urine or blood.
  • hCG is secreted by trophoblast cells after implantation.
  • Pregnancy test kits contain hCG antibodies → color change indicates pregnancy.

38. Explain the physiological changes in a woman during pregnancy.

Answer:

  • Uterine enlargement, breast development.
  • Increased blood volume, metabolic rate.
  • Hormonal changes (rise in hCG, progesterone, estrogen).
  • Emotional and physical adaptations for fetal growth.

39. What is gastrulation? Explain its importance.

Answer:

  • Process of forming three germ layers: ectoderm, mesoderm, and endoderm.
  • Occurs after implantation.
    Importance:
    • Marks beginning of tissue and organ formation.
    • Differentiates body structures.

40. Explain the significance of reproductive hormones in males.

Answer:

  • FSH: Sperm production.
  • LH: Testosterone secretion.
  • Testosterone: Growth of male organs, spermatogenesis, and secondary characters.
    Overall Role: Regulates sexual maturity and fertility.

41. Describe the role of hormones in parturition.

Answer:

  • Oxytocin: Triggers contractions.
  • Relaxin: Relaxes pelvic ligaments.
  • Estrogen & progesterone: Prepare uterus.
  • Prostaglandins: Intensify contractions.
    Mechanism: Positive feedback ensures complete delivery.

42. Explain IVF (Test Tube Baby) technology.

Answer:

  • Ova collected from mother → fertilized with sperm in lab → zygote cultured → implanted in uterus.
    Steps: Ovulation induction → Egg retrieval → Fertilization → Embryo transfer.
    Uses: Helps infertile couples conceive.

43. What are identical and fraternal twins?

Answer:

  • Identical (Monozygotic): From one zygote → genetically identical.
  • Fraternal (Dizygotic): From two ova fertilized by two sperms → genetically different.
    Significance: Demonstrate natural reproductive variation.

44. Explain the role of pituitary gland in reproduction.

Answer:

  • FSH & LH control gamete formation and hormone secretion.
  • Prolactin: Milk production.
  • Oxytocin: Uterine contraction and milk ejection.
    Coordination: Hypothalamic–pituitary–gonadal axis.

45. What is capacitation? Explain its significance.

Answer:

  • Physiological changes in sperm inside female tract.
  • Removes cholesterol and proteins from membrane → acrosomal reaction possible.
    Importance: Enables sperm to fertilize ovum.

46. Explain the process of cleavage in human embryo.

Answer:

  • Series of mitotic divisions in zygote without growth.
  • Produces morula and then blastocyst.
  • Occurs in fallopian tube.
    Purpose: Increases cell number and prepares for implantation.

47. Explain the role of hormones in lactation.

Answer:

  • Prolactin: Initiates milk synthesis.
  • Oxytocin: Causes milk ejection.
  • Estrogen & progesterone: Prepare mammary glands during pregnancy.
    Feedback mechanism: Suckling stimulates milk secretion.

48. Explain how sex of the child is determined in humans.

Answer:

  • Female: XX; Male: XY.
  • Female gamete always X; male gamete either X or Y.
  • If sperm contributes X → girl; Y → boy.
    Conclusion: Father determines sex of child.

49. Explain the role of progesterone in reproduction.

Answer:

  • Secreted by corpus luteum and placenta.
  • Maintains endometrium for implantation.
  • Inhibits uterine contraction.
  • Prepares mammary glands for lactation.
    Essential hormone of pregnancy.

50. Describe any five common reproductive disorders.

Answer:

1.   Amenorrhea: Absence of menstruation.

2.   Endometriosis: Growth of endometrial tissue outside uterus.

3.   Infertility: Inability to conceive.

4.   Impotence: Inability to achieve erection.

5.   PCOS: Hormonal imbalance causing cysts in ovaries.
Management: Hormonal therapy, surgery, or assisted reproduction.

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